Probaly one of the most famous cases of FD was that of Leon Fleisher. In the 50's he was a prominant concert pianist and had studied with Artur Schnabel. In the 60's he developed Focal Dystonia in his right hand though it was many years before he had that diagnosis. He continued to perform and record left-handed repertoire for the piano, while shifting his focus to his conducting career. In the last decade he returned to two-handed repertoire after receiving botox injections in his hand. The video on the right pretty much tells his whole story, and details the effects of the FD. There is also an in depth article in the Independent online.
See how focal dystonia affects different musicians